Learning Objective: To learn with examples the application of ion-dipole interactions in our daily lives.
Skill Level - Intermediate
Chapter: Intermolecular Forces
Sub-topic: Ion-Dipole Interactions
Author's Note: Health advocates voice the growing need to incorporate a diet rich in minerals which otherwise would pave the way to chronic conditions. These minerals are elements like Calcium, Sodium, Zinc, Magnesium, Iron, etc. in various forms that are absorbed in our small intestine using water as the polar medium. Such an absorption or other complex biochemical processes can only occur when these minerals in the form of ions interact using ion-dipole interactions. This section covers some of those applications which are crucial for existence. Henceforth, you will notice how intricately tied are such nonbonding interactions with our daily lives.
Importance of Ion - Dipole Interaction
Ion-dipole interactions determine the solubility of many ionic compounds in polar solvents. The phrase- 'like dissolves like' reiterates the rule that polar ions always dissolve in polar solvents.
In biological macromolecules, the ionic interaction with protein amino acids (CO-NH-containing groups) is highly important. The NH groups from both main chains and side chains of amino acids bind anions and negatively charged molecules. In contrast, the CO groups from both sources bind metallic cations and positively charged molecules.

Ion–dipoles can be used directly as a part of the catalysis....
An intermediate in the glycolysis....
Other essential utilities of ion-polar solvent interactions seen in everyday life are –
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